Please do not think that because you are depressed or someone else is depressed, that they or you are any less spiritual. More often than not, Spirituality has nothing to do with it. There are medical reasons for depression. There is the temperament connection; a melancholic is more prone to depression than a Phlegmatic. Sometimes it is stress and pressure. Great loss and grief can cause depression. Depression can be circumstantial and situational. There are certain Zones that people consistently enter into that deposits them in, keeps them in or leads them to depression.